Drug Delivery Systems Using Biotextiles: A Comprehensive Overview

Biotextiles as medical implants: 9. Drug delivery systems using biotextiles (Woodhead Publishing Series in Textiles)

by John Lindley

4.5 out of 5

Language	:	English
File size	:	1004 KB
Text-to-Speech	:	Enabled
Enhanced typesetting	:	Enabled
Print length	:	35 pages
Screen Reader	:	Supported

FREE

Biotextiles, a convergence of biology and textiles, have emerged as groundbreaking materials in the field of healthcare, particularly in drug delivery applications. Drug delivery systems using biotextiles offer unique advantages over traditional methods, including enhanced drug efficacy, targeted drug delivery, and improved patient comfort. This article delves into the advancements, applications, and future prospects of these innovative systems.

Advancements in Biotextile-Based Drug Delivery Systems

Biocompatible and Biodegradable Materials

Biotextiles are composed of biocompatible and biodegradable materials, such as natural polymers (e.g., collagen, silk fibroin) and synthetic polymers (e.g., polylactic acid, polyglycolic acid). These materials are well-tolerated by the body, reducing adverse reactions and ensuring patient safety.

Controlled Release Mechanisms

Drug delivery systems using biotextiles can be engineered to release drugs in a controlled manner. By incorporating drug carriers into the biotextile structure, drugs are gradually released over an extended period, providing sustained therapeutic effects with reduced dosing frequency.

Targeted Drug Delivery

Biotextiles enable targeted drug delivery by localizing the release of drugs to specific anatomical sites or diseased tissues. This approach minimizes systemic side effects, maximizes therapeutic efficacy, and optimizes drug utilization.

Applications of Biotextile-Based Drug Delivery Systems

Tissue Engineering and Wound Healing

Biotextiles serve as scaffolds for tissue regeneration and wound healing applications. By incorporating growth factors and other bioactive agents, biotextiles promote cell proliferation, matrix formation, and the restoration of damaged tissue.

Cancer Treatment

Drug delivery systems using biotextiles show promise in cancer treatment. They can deliver chemotherapy drugs directly to tumor sites, reducing systemic toxicity and enhancing therapeutic efficacy. They also facilitate the controlled release of targeted therapies, improving patient outcomes.

Chronic Disease Management

Biotextile-based drug delivery systems offer a solution for chronic disease management. They can deliver drugs continuously over prolonged periods, improving adherence and ensuring effective disease control. Examples include insulin delivery for diabetes and pain management for chronic conditions.

Future Prospects of Biotextile-Based Drug Delivery Systems

Personalized Medicine

The integration of biotextiles with biosensors and microfluidics enables the development of personalized drug delivery systems. These systems can monitor patient-specific parameters, adjust drug release profiles, and optimize therapeutic outcomes.

Regenerative Medicine

Biotextiles hold great potential in regenerative medicine. They provide a supportive matrix for cell growth and differentiation, facilitating the development of functional tissues and organs for transplantation.

Smart Textiles

The advancement of wearable technologies has led to the development of smart textiles that can deliver drugs and monitor patient health. These textiles integrate sensors, actuators, and drug delivery systems, providing real-time monitoring and personalized drug delivery.

Drug delivery systems using biotextiles represent a paradigm shift in healthcare. Their ability to enhance drug efficacy, target drug delivery, and improve patient comfort makes them a promising solution for various therapeutic applications. As research and development continue, biotextile-based drug delivery systems are poised to revolutionize the delivery of drugs and transform patient outcomes.

Biotextiles as medical implants: 9. Drug delivery systems using biotextiles (Woodhead Publishing Series in Textiles)

by John Lindley

4.5 out of 5

Language	:	English
File size	:	1004 KB
Text-to-Speech	:	Enabled
Enhanced typesetting	:	Enabled
Print length	:	35 pages
Screen Reader	:	Supported

FREE